Dopamine  

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-{{Template}}A [[neurotransmitter]] associated with [[movement]], [[attention]], [[learning]], and the [[brain]]'s [[pleasure]] and [[reward]] system.+{{Template}}
 +A [[neurotransmitter]] associated with [[movement]], [[attention]], [[learning]], and the [[brain]]'s [[pleasure]] and [[reward]] system.
 + 
 +==History==
 +Dopamine was first synthesized in 1910 by [[George Barger]] and [[James Ewens]] at [[Wellcome Trust|Wellcome]] Laboratories in London, England. It was named dopamine because it is a [[monoamine]] whose [[Precursor chemical|precursor]] in the Barger-Ewens synthesis is 3,4-''d''ihydr''o''xy''p''henyl''a''lanine (levodopamine or [[L-DOPA]]). Dopamine's function as a neurotransmitter was first recognized in 1958 by [[Arvid Carlsson]] and [[Nils-Åke Hillarp]] at the Laboratory for Chemical Pharmacology of the National Heart Institute of [[Sweden]]. Carlsson was awarded the 2000 [[Nobel Prize in Physiology or Medicine]] for showing that dopamine is not only a precursor of [[norepinephrine]] (noradrenaline) and [[epinephrine]] (adrenaline), but also a neurotransmitter.
 + 
 +== See also ==
 +* [[Substance use disorder|Addiction]]
 +* [[Amphetamine]]
 +* [[Antipsychotic]]
 +* [[Catecholamine]]
 +* [[Catechol-O-methyl transferase]]
 +* [[Classical conditioning]]
 +* [[Cocaine]]
 +* [[Depression (mood)|Depression]]
 +* [[Dopamine hypothesis of schizophrenia]]
 +* [[Dopamine reuptake inhibitor]]
 +* [[Epinine]] (N-methyldopamine)
 +* [[Limbic system]]
 +* [[Methylphenidate]]
 +* [[N,N-Dimethyldopamine]]
 +* [[Neurotransmitter]]
 +* [[Operant conditioning]]
 +* [[Parkinson's disease]]
 +* [[Prolactinoma]]
 +* [[Schizophrenia]]
 +* [[Selegiline]]
 +* [[Serotonin]]
 + 
{{GFDL}} {{GFDL}}

Revision as of 16:45, 3 October 2013

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A neurotransmitter associated with movement, attention, learning, and the brain's pleasure and reward system.

History

Dopamine was first synthesized in 1910 by George Barger and James Ewens at Wellcome Laboratories in London, England. It was named dopamine because it is a monoamine whose precursor in the Barger-Ewens synthesis is 3,4-dihydroxyphenylalanine (levodopamine or L-DOPA). Dopamine's function as a neurotransmitter was first recognized in 1958 by Arvid Carlsson and Nils-Åke Hillarp at the Laboratory for Chemical Pharmacology of the National Heart Institute of Sweden. Carlsson was awarded the 2000 Nobel Prize in Physiology or Medicine for showing that dopamine is not only a precursor of norepinephrine (noradrenaline) and epinephrine (adrenaline), but also a neurotransmitter.

See also




Unless indicated otherwise, the text in this article is either based on Wikipedia article "Dopamine" or another language Wikipedia page thereof used under the terms of the GNU Free Documentation License; or on research by Jahsonic and friends. See Art and Popular Culture's copyright notice.

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