From The Art and Popular Culture Encyclopedia
Since 1996, Myles has appeared in a number of both American and English films and television productions. In 2001, she got a small role as Johnny Depp's wife, Victoria Abberline, in the thriller film From Hell. She had a supporting role in the 2003 film Underworld and in sequel Underworld: Evolution (in a brief flashback scene). In 2003, she played the schoolgirl lead in the thriller Out of Bounds and she also played Lady Penelope in the Thunderbirds. In 2006, Myles co-starred with actor James Franco in the romantic drama Tristan + Isolde, playing the role of Isolde.
Myles appeared as Madame de Pompadour in a 2006 episode of Doctor Who, "The Girl in the Fireplace". She co-starred opposite English actor Max Minghella, playing his love interest in 2006's quirky comedy Art School Confidential. Also in 2006, Myles appeared in a BBC TV adaptation of Dracula; she played Lucy Westenra alongside Marc Warren, David Suchet and Dan Stevens. As of 2007, she filmed Outlander with James Caviezel and Jack Huston, played the role of Freya.
She has received Best Actress in 2007 for her role in Hallam Foe from the British Independent Film Award committee as well as the BAFTA Scotland Award. Her series, Moonlight, won for Best New Drama in the 2007 People's Choice Awards.