Paralysis
From The Art and Popular Culture Encyclopedia
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Paralysis is the complete loss of muscle function for one or more muscle groups. Paralysis often includes loss of feeling in the affected area.
Paralysis in the animal world
Many animal species use paralyzing toxins to capture prey, evade predation, or both. A well-known example is the tetrodotoxin of fish species such as Takifugu rubripes, the famously lethal pufferfish of Japanese fugu. This toxin works by binding to sodium channels in nerve cells, preventing the cells' proper function. A non-lethal dose of this toxin results in temporary paralysis. This toxin is also present in many other species ranging from toads to nemerteans. Another interesting use of paralysis in the natural world is the behavior of some species of wasp. To complete the reproductive cycle, the female wasp paralyzes a prey item such as a grasshopper and places it in her nest. She then lays eggs in the paralyzed insect, which is devoured by the larvae when they hatch. Many snakes also exhibit powerful neurotoxins that can cause non-permanent paralysis or death.
Paralysis can be seen in breeds of dogs that are chondrodysplastic. These dogs have short legs, and may also have short muzzles. Their intervertebral disc material can calcify and become more brittle. In such cases, the disc may rupture, with disc material ending up in the spinal canal, or rupturing more laterally to press on spinal nerves. A minor rupture may only result in paresis, but a major rupture can cause enough damage to cut off circulation. If no signs of pain can be elicited, surgery should be performed within 24 hours of the incident, to remove the disc material and relieve pressure on the spinal cord. After 24 hours, the chance of recovery declines rapidly, since with continued pressure, the spinal cord tissue deteriorates and dies.
Another type of paralysis is caused by a fibrocartilaginous embolism. This is a microscopic piece of disc material that breaks off and becomes lodged in a spinal artery. Nerves served by the artery will die when deprived of blood.
The German Shepherd is especially prone to developing degenerative myelopathy. This is a deterioration of nerves in the spinal cord, starting in the posterior part of the cord. Dogs so affected will become gradually weaker in the hind legs as nerves die off. Eventually their hind legs become useless. They often also exhibit fecal and urinary incontinence. As the disease progresses, the paresis and paralysis gradually move forward. This disease also affects other large breeds of dogs. It is suspected to be an autoimmune problem.
Cats with a heart murmur may develop blood clots that travel through arteries. If a clot is large enough to block one or both femoral arteries, there may be hind leg paralysis because the major source of blood flow to the hind leg is blocked.
See also
- Spinal cord injuries
- Paraplegia
- Quadriplegia
- Muscle relaxant
- Petrifaction
- Ptosis
- Sleep paralysis
- Hemiparesis
- Beriberi
- Locked-in syndrome
- Neuroprosthetics
- Brain-computer interface
- Tonic immobility
- Transfixation
- Cerebral palsy
- Cobra Toxin
- Obdormition
