From The Art and Popular Culture Encyclopedia
La Défense is a major business district for the city of Paris (French:"Ville de Paris"), bordering Neuilly-sur-Seine, west of the city itself. It is centered in an ovular freeway loop straddling the Hauts-de-Seine département municipalities of Nanterre, Courbevoie and Puteaux. The district is at the westernmost extremity of Paris' 10-km long Historical Axis, which starts at the Louvre in Downtown Paris and crosses the Champs-Élysées and the Arc de Triomphe.
Around its 100 m-high Grande Arche and esplanade ("le Parvis"), this district holds many of the Paris urban area's tallest high-rises: with its 77.5 acres, its 72 glass-and-steel slick buildings including 14 high-rises above 150 m, its 150 000 daily workers and 3.5 million square meters of office space. La Défense is Europe's largest district specifically built for business.