| Year
| Film
| Role
| Notes
|
| 1984
| Template:Sortname
| Carmen Engler
|
|
1985– 1988, 1986– 1988
| As the World Turns
| Frannie Hughes Sabrina Hughes
| Daytime Emmy Award for Outstanding Younger Actress in a Drama Series
|
| 1987
| I'll Take Manhattan
| India West
|
|
| 1990
| Tales from the Darkside: The Movie
| Susan
|
|
| 1990
| An Adult Comedy
| Lead
| TV Pilot, produced by Sarah Lawson
|
| 1991
| Cast a Deadly Spell
| Connie Stone
|
|
| 1992
| Template:Sortname
| Marlene Craven
| Nominated—Saturn Award for Best Supporting Actress
|
| 1992
| Template:Sortname
| Elinor
|
|
| 1993
| Body of Evidence
| Sharon Dulaney
|
|
| 1993
| Benny & Joon
| Ruthie
|
|
| 1993
| Template:Sortname
| Dr. Anne Eastman
|
|
| 1993
| Short Cuts
| Marian Wyman
| Golden Globe Special Ensemble Award Volpi Cup Nominated—Independent Spirit Award for Best Supporting Female
|
| 1994
| Vanya on 42nd Street
| Yelena
| Boston Society of Film Critics Award for Best Actress Nominated—Chlotrudis Award for Best Actress
|
| 1995
| Roommates
| Beth Holzcek
|
|
| 1995
| Safe
| Carol White
| Nominated—Chlotrudis Award for Best Actress Nominated—Independent Spirit Award for Best Lead Female
|
| 1995
| Nine Months
| Rebecca Taylor
|
|
| 1995
| Assassins
| Electra
|
|
| 1996
| Surviving Picasso
| Dora Maar
|
|
| 1997
| Template:Sortname
| Dr. Sarah Harding
| Nominated—Blockbuster Entertainment Award for Favorite Actress – Sci-Fi
|
| 1997
| Template:Sortname
| Mia
| Nominated—Online Film Critics Society Award for Best Supporting Actress
|
| 1997
| Boogie Nights
| Amber Waves
| Florida Film Critics Circle Award for Best Supporting Actress Florida Film Critics Circle Award for Best Cast National Society of Film Critics Award for Best Supporting Actress Satellite Award for Best Supporting Actress – Motion Picture Nominated—Academy Award for Best Supporting Actress Nominated—Chlotrudis Award for Best Supporting Actress (also for The Myth of Fingerprints) Nominated—Golden Globe Award for Best Supporting Actress – Motion Picture Nominated—Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Supporting Role Nominated—Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture
|
| 1998
| Template:Sortname
| Maude Lebowski
| Nominated—Satellite Award for Best Supporting Actress – Motion Picture
|
| 1998
| Hellcab
| Distraught Woman
|
|
| 1998
| Psycho
| Lila Crane
|
|
| 1999
| Cookie's Fortune
| Cora Duvall
| Dallas-Fort Worth Film Critics Association Award for Best Supporting Actress
|
| 1999
| Template:Sortname
| Mrs. Laura Cheveley
| Nominated—Chicago Film Critics Association Award for Best Supporting Actress Nominated—Golden Globe Award for Best Actress – Motion Picture Musical or Comedy Nominated—Satellite Award for Best Actress – Motion Picture Musical or Comedy
|
| 1999
| Template:Sortname
| Theresa Collins
|
|
| 1999
| Template:Sortname
| Sarah Miles
| Nominated—Academy Award for Best Actress Nominated—BAFTA Award for Best Actress in a Leading Role Nominated—Chicago Film Critics Association Award for Best Actress Nominated—Chlotrudis Award for Best Actress (also for An Ideal Husband) Nominated—Golden Globe Award for Best Actress – Motion Picture Drama Nominated—London Film Critics Circle Award for Best Actress Nominated—Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Leading Role
|
| 1999
| Magnolia
| Linda Partridge
| Florida Film Critics Circle Award for Best Cast National Board of Review Award for Best Supporting Actress National Board of Review Award for Best Cast Nominated—Online Film Critics Society Award for Best Supporting Actress Nominated—Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Supporting Role Nominated—Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture Nominated—Blockbuster Entertainment Award for Favorite Supporting Actress – Drama
|
| 2000
| Template:Sortname
| Audrey
|
|
| 2000
| Not I
| Mouth
|
|
| 2001
| Hannibal
| Agent Clarice Starling
| Nominated—Saturn Award for Best Actress
|
| 2001
| Evolution
| Dr. Allison Reed
|
|
| 2001
| Template:Sortname
| Wavey Prowse
|
|
| 2001
| World Traveler
| Dulcie
|
|
| 2002
| Far from Heaven
| Cathy Whitaker
| Broadcast Film Critics Association Award for Best Actress Chicago Film Critics Association Award for Best Actress Chlotrudis Award for Best Actress Dallas-Fort Worth Film Critics Association Award for Best Actress Florida Film Critics Circle Award for Best Actress Independent Spirit Award for Best Lead Female Kansas City Film Critics Circle Award for Best Actress London Film Critics Circle Award for Best Actress Los Angeles Film Critics Association Award for Best Actress (also for The Hours) National Board of Review Award for Best Actress Online Film Critics Society Award for Best Actress Phoenix Film Critics Society Award for Best Actress San Diego Film Critics Society Award for Best Actress Seattle Film Critics Association Award for Best Actress Southeastern Film Critics Association Award for Best Actress Toronto Film Critics Association Award for Best Actress Vancouver Film Critics Circle Award for Best Actress Washington D.C. Area Film Critics Association for Best Actress Volpi Cup Nominated—Academy Award for Best Actress Nominated—Empire Award for Best Actress Nominated—Golden Globe Award for Best Actress – Motion Picture Drama Nominated—Satellite Award for Best Actress – Motion Picture Drama Nominated—Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Leading Role
|
| 2002
| Template:Sortname
| Laura Brown
| Silver Bear for Best Actress (shared with Meryl Streep and Nicole Kidman) Los Angeles Film Critics Association Award for Best Actress (also for Far from Heaven) Nominated—Academy Award for Best Supporting Actress Nominated—BAFTA Award for Best Actress in a Supporting Role Nominated—Chicago Film Critics Association Award for Best Supporting Actress Nominated—Las Vegas Film Critics Society Award for Best Supporting Actress Nominated—Phoenix Film Critics Society Award for Best Cast Nominated—Satellite Award for Best Actress – Motion Picture Drama Nominated—Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture Nominated—Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Supporting Role
|
| 2004
| Marie and Bruce
| Marie
|
|
| 2004
| Laws of Attraction
| Audrey Woods
|
|
| 2004
| Template:Sortname
| Telly Paretta
| Nominated—Saturn Award for Best Actress
|
| 2005
| Template:Sortname
| Evelyn Ryan
| Nominated—Satellite Award for Best Actress – Motion Picture Drama
|
2005, 2007
| Template:Sortname
| Herself
| Cameo in the initial 2005 indie-film festival winner, which later became the pilot for the 2007 TV series The Naked Brothers Band, created by her celebrity family-friend, the actress Polly Draper.
|
| 2006
| Freedomland
| Brenda Martin
|
|
| 2006
| Trust the Man
| Rebecca
|
|
| 2006
| Children of Men
| Julian
|
|
| 2007
| Next
| Callie Ferris
|
|
| 2007
| I'm Not There
| Alice
|
|
| 2008
| Savage Grace
| Barbara Daly Baekeland
|
|
| 2008
| Eagle Eye
| ARIIA
| (voice) (uncredited)
|
| 2008
| Blindness
| Doctor's Wife
| Nominated—Saturn Award for Best Actress
|
| 2009
| Shelter
| Cara
|
|
| 2009
| Template:Sortname
| Kat
|
|
| 2009
| Template:Sortname
| Charlotte
| Hollywood Film Festival Best Supporting Actress Nominated—Broadcast Film Critics Association Award for Best Supporting Actress Nominated—Chicago Film Critics Association Award for Best Supporting Actress Nominated—Chlotrudis Award for Best Supporting Actress Nominated—Golden Globe Award for Best Supporting Actress – Motion Picture Nominated—Washington D.C. Area Film Critics Association for Best Supporting Actress
|
| 2009
| Chloe
| Catherine
|
|
| 2009
| 30 Rock
| Nancy Donovan
| Episodes: "Secret Santa", "Winter Madness", "Lee Marvin vs. Derek Jeter", "Emanuelle Goes to Dinosaur Land", and "I Do Do"
|
| 2010
| Template:Sortname
| Jules
|
|
| 2010
| Boone's Lick
| Mary Margaret
| in pre-production
|