Influx of disease in the Caribbean  

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First European contact in 1492 started an influx of disease into the Caribbean. Diseases originating in Europe and Africa came to North America for the first time, resulting in demographic and sociopolitical changes. The indigenous Caribbeans had little immunity to the predominantly European diseases, resulting in significant loss of life and contributing to their enslavement and exploitation. Enslaved Africans were brought to replace the dwindling indigenous population, solidifying the position of disease in triangular trade.

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