Genome editing
From The Art and Popular Culture Encyclopedia
|
Related e |
|
Featured: |
Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site specific locations.
In 2018, the common methods for such editing used engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations ('edits').
[edit]
See also
- CRISPR/Cpf1
- Epigenome editing
- Germinal choice technology
- NgAgo, a ssDNA-guided Argonaute endonuclease
Unless indicated otherwise, the text in this article is either based on Wikipedia article "Genome editing" or another language Wikipedia page thereof used under the terms of the GNU Free Documentation License; or on research by Jahsonic and friends. See Art and Popular Culture's copyright notice.
