Cocaine dependence
From The Art and Popular Culture Encyclopedia
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Cocaine dependence (or addiction) is psychological dependency on the regular use of cocaine. It can result in cardiovascular and brain damage, specifically in the central nervous system.
The use of cocaine, depending of the severity, can cause mood swings, paranoia, insomnia, psychosis, high blood pressure, tachycardia, panic attacks, cognitive impairments and drastic changes in the personality that can lead to aggressive, compulsive, criminal and/or erratic behaviors.
The symptoms of cocaine withdrawal (also known as comedown or crash) range from moderate to severe: dysphoria, depression, anxiety, psychological and physical weakness, pain and compulsive craving.
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See also
- SB-277011-A - a dopamine D3 receptor antagonist, used in the study of cocaine addiction. Where cocaine reduces the threshold for brain electrical self-stimulation in rats, an indication of cocaine's rewarding effects, SB-277011-A completely reverses this effect.
Unless indicated otherwise, the text in this article is either based on Wikipedia article "Cocaine dependence" or another language Wikipedia page thereof used under the terms of the GNU Free Documentation License; or on research by Jahsonic and friends. See Art and Popular Culture's copyright notice.
