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Gregory Markopoulos (March 12 1928 - November 12 1992) was an American experimental filmmaker. Born in Toledo, Ohio to Greek immigrant parents, Markopoulos began making 8 mm films at an early age. He attended USC Film School in the late 1940's, and went on to become a notable member of the New American Cinema movement, a contributor to Film Culture magazine, and an instructor at the Art Institute of Chicago. In 1967, he and his partner Robert Beavers left the United States for permanent residence in Europe. Once ensconced in self-imposed exile, Markopoulos withdrew his films from circulation, refused any interviews, and insisted that a chapter about him be removed from the 2nd edition of Visionary Film, P. Adams Sitney's seminal study of American Avant-Garde Cinema. While he continued to make films, his work went largely unseen for almost thirty years.

Selected filmography

• Psyche (1947)
• Flowers of Asphalt (1951)
• Serenity (1962)
• Twice a Man (1964)
• Ming Green (1966)
• Galaxie (1966)
• Through a Lens Brightly: Mark Turbyfill (1967)
• Himself As Herself (1967)
• The Illiac Passion (1968)